FAQs

Frequently asked questions about VIBERZI and Irritable Bowel Syndrome with Diarrhea (IBS‑D)

In clinical studies, constipation occurred in 8% of people taking VIBERZI. Severe constipation occurred in less than 1% of people. Stop taking VIBERZI and call your doctor if you have constipation that lasts more than 4 days.

VIBERZI was studied in 2 clinical trials involving more than 2400 men and women, ages 18-80.

It is not known if VIBERZI is safe and effective in children. VIBERZI is a prescription medicine used to treat adults who have IBS‑D.

Patients aged 65 years and older were included in the clinical trials. No overall differences in effectiveness were observed between adults aged 65 years and older and younger people. People aged 65 years and older had an increased number of side effects, including serious side effects, compared to people younger than age 65.

Always talk to your doctor about other medicines you might be taking. In clinical studies, people could take Imodium® as needed while also taking VIBERZI. If you are taking VIBERZI, you may take Imodium® occasionally to treat severe diarrhea, but avoid long-term use. Stop taking Imodium® right away if you become constipated.

Trademarks are owned by their respective companies.

Imodium® and Pepto‑Bismol™ are over-the-counter medicines for occasional use. VIBERZI is a prescription medicine that is FDA-approved for daily use in adults with IBS‑D to reduce diarrhea and abdominal pain at the same time.

Trademarks are owned by their respective companies.

VIBERZI is a federally controlled substance because it may be abused or lead to dependence. It has been designated as a substance which has a low potential for abuse and a low risk of dependence.

Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Maximum savings limit applies; patient out-of-pocket expense may vary. Please see full Program Terms, Conditions, and Eligibility Criteria at ViberziSavings.com.

Next: VIBERZI Savings Program 

Important Risk Information

VIBERZI can cause serious side effects, including:

Stop taking VIBERZI and call your doctor if you have new or worsening stomach-area (abdomen) pain or pain in the upper right side of your stomach-area that may move to your back or shoulder, with or without nausea and vomiting.

Do not take VIBERZI if you:

Before taking VIBERZI, tell your doctor about all of your medical conditions, including if you do not have a gallbladder, have liver problems, or are nursing, pregnant, or plan to become pregnant.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. If you are taking VIBERZI you should not take medicines that cause constipation, including: Lotronex® (alosetron), anticholinergic medicines, and opioid pain medicines.

Side effects

The most common side effects of VIBERZI include constipation, nausea, and abdominal pain. Stop taking VIBERZI and call your doctor if you have constipation that lasts more than 4 days. These are not all the possible side effects of VIBERZI. Call your doctor for medical advice about side effects.

For further information, please talk to your healthcare professional and see accompanying Patient Medication Guide and full Prescribing Information.

What is VIBERZI?

VIBERZI is a prescription medicine used to treat adults who have Irritable Bowel Syndrome with Diarrhea (IBS-D).

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Important Risk Information

VIBERZI can cause serious side effects, including:
  • A spasm in a muscle of the digestive system (called the sphincter of Oddi), which may cause new or worsening abdominal pain. Your risk of having a spasm is increased if you do not have a gallbladder. This spasm usually happens within the first week of treatment and usually goes away when treatment is stopped.
  • Inflammation of the pancreas (called pancreatitis). Symptoms of pancreatitis usually go away when treatment with VIBERZI is stopped. Your risk of getting pancreatitis is increased if you drink more than 3 alcoholic drinks a day.

Stop taking VIBERZI and call your doctor if you have new or worsening stomach-area (abdomen) pain or pain in the upper right side of your stomach-area that may move to your back or shoulder, with or without nausea and vomiting.

Do not take VIBERZI if you:
  • Have or may have had a blockage in your gallbladder or a sphincter of Oddi problem
  • Have or had problems with alcohol abuse, alcohol addiction, or drink more than 3 alcoholic drinks a day
  • Have had pancreatitis or other pancreas problems, including if you have had or may have had a blockage in your pancreas
  • Have severe liver problems
  • Have had long-lasting (chronic) or severe constipation, or problems caused by constipation
  • Have or may have had a bowel blockage (intestinal obstruction)

Before taking VIBERZI, tell your doctor about all of your medical conditions, including if you do not have a gallbladder, have liver problems, or are nursing, pregnant, or plan to become pregnant.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. If you are taking VIBERZI you should not take medicines that cause constipation, including: Lotronex® (alosetron), anticholinergic medicines, and opioid pain medicines.

Side effects

The most common side effects of VIBERZI include constipation, nausea, and abdominal pain. Stop taking VIBERZI and call your doctor if you have constipation that lasts more than 4 days. These are not all the possible side effects of VIBERZI. Call your doctor for medical advice about side effects.

For further information, please talk to your healthcare professional and see accompanying Patient Medication Guide and full Prescribing Information.

What is VIBERZI?

VIBERZI is a prescription medicine used to treat adults who have Irritable Bowel Syndrome with Diarrhea (IBS-D).